Keytruda Market Insights 2025, Analysis and Forecast to 2030, by Manufacturers, Regions, Technology, Application, Product Type

By: HDIN Research Published: 2025-05-25 Pages: 74
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Keytruda Market Summary
Introduction and Market Overview
Keytruda (pembrolizumab), a PD-1 inhibitor, treats cancers including melanoma, lung cancer (NSCLC), head and neck cancer, breast cancer, Hodgkin lymphoma, gastric cancer, urothelial cancer, and others, with global cancer cases reaching 19.3 million in 2020 and projected to hit 30 million by 2030. The market is driven by rising cancer incidence, with NSCLC comprising 85% of lung cancers, and Keytruda’s superior efficacy, boosting NSCLC 5-year survival from 5% to 20%. Combination therapies, such as Keytruda with mRNA-4157 (reducing melanoma mortality by 65%), and 40 FDA-approved indications by 2024, including endometrial cancer, fuel growth. Accelerated approvals by FDA, EMA, and China’s NMPA, with 70% OECD reimbursement, further propel the market. The global Keytruda market is estimated at USD 16-30 billion in 2025, with a CAGR of 3%-5% through 2030.

Regional Market Trends
 North America: The U.S. leads with high cancer prevalence and Keytruda adoption, while Canada emphasizes immunotherapy access.
 Europe: Germany, France, and the UK drive growth with advanced oncology care.
 Asia Pacific: China and Japan see rising cancer cases, with India focusing on biosimilars.
 Rest of the World: Brazil enhances oncology infrastructure, while the Middle East addresses breast and gastric cancers.

Application Analysis
 Melanoma: Expected growth of 3.5%-5.5%, driven by rising incidence. Trends focus on combination therapies.
 Lung Cancer: Projected growth of 3.8%-5.8%, linked to NSCLC prevalence. Advances emphasize PD-1 efficacy.
 Head & Neck Cancer: Anticipated growth of 3.2%-5.2%, for advanced cases. Trends highlight immunotherapy adoption.
 Breast Cancer: Expected growth of 3.6%-5.6%, targeting triple-negative cases. Developments prioritize PFS improvement.
 Hodgkin Lymphoma: Projected growth of 3.0%-5.0%, for relapsed cases. Trends focus on pediatric applications.
 Gastric Cancer: Anticipated growth of 3.3%-5.3%, for metastatic cases. Advances emphasize combination regimens.
 Urothelial Cancer: Expected growth of 3.4%-5.4%, with new indications. Trends highlight PADCEV combinations.
 Others: Projected growth of 3.1%-5.1%, covering emerging indications. Developments prioritize novel cancers.

Distribution Channel Analysis
 Hospital Pharmacy: Expected growth of 3.5%-5.5%, driven by inpatient oncology care. Trends focus on specialized delivery.
 Specialty Pharmacy: Projected growth of 3.8%-5.8%, linked to outpatient immunotherapy. Advances emphasize patient access.

Key Market Players
 Merck: Pioneers Keytruda for multiple cancers.
 Bristol-Myers Squibb Company: Develops competing PD-1 inhibitors.
 Samsung Bioepis: Focuses on Keytruda biosimilars.
 Bio-Thera Solutions: Innovates in biosimilar immunotherapies.

Porter’s Five Forces Analysis
 Threat of New Entrants: Low, due to high R&D costs and stringent regulatory requirements.
 Threat of Substitutes: Moderate, with other immunotherapies competing, but Keytruda’s broad indications are unique.
 Bargaining Power of Buyers: Moderate, as insurers negotiate prices, but limited PD-1 options strengthen providers.
 Bargaining Power of Suppliers: Low, with multiple suppliers of active ingredients.
 Competitive Rivalry: High, with companies competing on indications, efficacy, and biosimilar development.

Market Opportunities and Challenges
Opportunities:
 Addressing 19.3 million annual cancer cases, projected to reach 30 million by 2030.
 Improving NSCLC 5-year survival to 20%.
 Leveraging combination therapies, reducing melanoma mortality by 65%.
 Expanding 40 FDA-approved indications.
 Benefiting from 70% OECD reimbursement coverage.
 Targeting emerging markets like China with new approvals.
Challenges:
 High costs of Keytruda limiting access.
 Competition from biosimilars post-patent expiry.
 Regulatory delays for new indications.
 Side effects of immunotherapy requiring monitoring.
 Limited oncology infrastructure in low-income regions.
Table of Contents
Chapter 1 Executive Summary
Chapter 2 Abbreviation and Acronyms
Chapter 3 Preface
3.1 Research Scope
3.2 Research Sources
3.2.1 Data Sources
3.2.2 Assumptions
3.3 Research Method
Chapter 4 Market Landscape
4.1 Market Overview
4.2 Classification/Types
4.3 Application/End Users
Chapter 5 Market Trend Analysis
5.1 Introduction
5.2 Drivers
5.3 Restraints
5.4 Opportunities
5.5 Threats
Chapter 6 Industry Chain Analysis
6.1 Upstream/Suppliers Analysis
6.2 Keytruda Analysis
6.2.1 Technology Analysis
6.2.2 Cost Analysis
6.2.3 Market Channel Analysis
6.3 Downstream Buyers/End Users
Chapter 7 Latest Market Dynamics
7.1 Latest News
7.2 Merger and Acquisition
7.3 Planned/Future Project
7.4 Policy Dynamics
Chapter 8 Historical and Forecast Keytruda Market in North America (2020-2030)
8.1 Keytruda Market Size
8.2 Keytruda Market by End Use
8.3 Competition by Players/Suppliers
8.4 Keytruda Market Size by Type
8.5 Key Countries Analysis
8.5.1 United States
8.5.2 Canada
8.5.3 Mexico
Chapter 9 Historical and Forecast Keytruda Market in South America (2020-2030)
9.1 Keytruda Market Size
9.2 Keytruda Market by End Use
9.3 Competition by Players/Suppliers
9.4 Keytruda Market Size by Type
9.5 Key Countries Analysis
9.5.1 Brazil
9.5.2 Argentina
9.5.3 Chile
9.5.4 Peru
Chapter 10 Historical and Forecast Keytruda Market in Asia & Pacific (2020-2030)
10.1 Keytruda Market Size
10.2 Keytruda Market by End Use
10.3 Competition by Players/Suppliers
10.4 Keytruda Market Size by Type
10.5 Key Countries Analysis
10.5.1 China
10.5.2 India
10.5.3 Japan
10.5.4 South Korea
10.5.5 Southest Asia
10.5.6 Australia
Chapter 11 Historical and Forecast Keytruda Market in Europe (2020-2030)
11.1 Keytruda Market Size
11.2 Keytruda Market by End Use
11.3 Competition by Players/Suppliers
11.4 Keytruda Market Size by Type
11.5 Key Countries Analysis
11.5.1 Germany
11.5.2 France
11.5.3 United Kingdom
11.5.4 Italy
11.5.5 Spain
11.5.6 Belgium
11.5.7 Netherlands
11.5.8 Austria
11.5.9 Poland
11.5.10 Russia
Chapter 12 Historical and Forecast Keytruda Market in MEA (2020-2030)
12.1 Keytruda Market Size
12.2 Keytruda Market by End Use
12.3 Competition by Players/Suppliers
12.4 Keytruda Market Size by Type
12.5 Key Countries Analysis
12.5.1 Egypt
12.5.2 Israel
12.5.3 South Africa
12.5.4 Gulf Cooperation Council Countries
12.5.5 Turkey
Chapter 13 Summary For Global Keytruda Market (2020-2025)
13.1 Keytruda Market Size
13.2 Keytruda Market by End Use
13.3 Competition by Players/Suppliers
13.4 Keytruda Market Size by Type
Chapter 14 Global Keytruda Market Forecast (2025-2030)
14.1 Keytruda Market Size Forecast
14.2 Keytruda Application Forecast
14.3 Competition by Players/Suppliers
14.4 Keytruda Type Forecast
Chapter 15 Analysis of Global Key Vendors
15.1 Merck
15.1.1 Company Profile
15.1.2 Main Business and Keytruda Information
15.1.3 SWOT Analysis of Merck
15.1.4 Merck Keytruda Sales, Revenue, Price and Gross Margin (2020-2025)
15.2 Bristol-Myers Squibb Company
15.2.1 Company Profile
15.2.2 Main Business and Keytruda Information
15.2.3 SWOT Analysis of Bristol-Myers Squibb Company
15.2.4 Bristol-Myers Squibb Company Keytruda Sales, Revenue, Price and Gross Margin (2020-2025)
Please ask for sample pages for full companies list
Table Abbreviation And Acronyms
Table Research Scope Of Keytruda Report
Table Data Sources Of Keytruda Report
Table Major Assumptions Of Keytruda Report
Table Keytruda Classification
Table Keytruda Applications
Table Drivers Of Keytruda Market
Table Restraints Of Keytruda Market
Table Opportunities Of Keytruda Market
Table Threats Of Keytruda Market
Table Raw Materials Suppliers
Table Different Production Methods Of Keytruda
Table Cost Structure Analysis Of Keytruda
Table Key End Users
Table Latest News Of Keytruda Market
Table Merger And Acquisition
Table Planned/Future Project Of Keytruda Market
Table Policy Of Keytruda Market
Table 2020-2030 North America Keytruda Market Size
Table 2020-2030 North America Keytruda Market Size By Application
Table 2020-2025 North America Keytruda Key Players Revenue
Table 2020-2025 North America Keytruda Key Players Market Share
Table 2020-2030 North America Keytruda Market Size By Type
Table 2020-2030 United States Keytruda Market Size
Table 2020-2030 Canada Keytruda Market Size
Table 2020-2030 Mexico Keytruda Market Size
Table 2020-2030 South America Keytruda Market Size
Table 2020-2030 South America Keytruda Market Size By Application
Table 2020-2025 South America Keytruda Key Players Revenue
Table 2020-2025 South America Keytruda Key Players Market Share
Table 2020-2030 South America Keytruda Market Size By Type
Table 2020-2030 Brazil Keytruda Market Size
Table 2020-2030 Argentina Keytruda Market Size
Table 2020-2030 Chile Keytruda Market Size
Table 2020-2030 Peru Keytruda Market Size
Table 2020-2030 Asia & Pacific Keytruda Market Size
Table 2020-2030 Asia & Pacific Keytruda Market Size By Application
Table 2020-2025 Asia & Pacific Keytruda Key Players Revenue
Table 2020-2025 Asia & Pacific Keytruda Key Players Market Share
Table 2020-2030 Asia & Pacific Keytruda Market Size By Type
Table 2020-2030 China Keytruda Market Size
Table 2020-2030 India Keytruda Market Size
Table 2020-2030 Japan Keytruda Market Size
Table 2020-2030 South Korea Keytruda Market Size
Table 2020-2030 Southeast Asia Keytruda Market Size
Table 2020-2030 Australia Keytruda Market Size
Table 2020-2030 Europe Keytruda Market Size
Table 2020-2030 Europe Keytruda Market Size By Application
Table 2020-2025 Europe Keytruda Key Players Revenue
Table 2020-2025 Europe Keytruda Key Players Market Share
Table 2020-2030 Europe Keytruda Market Size By Type
Table 2020-2030 Germany Keytruda Market Size
Table 2020-2030 France Keytruda Market Size
Table 2020-2030 United Kingdom Keytruda Market Size
Table 2020-2030 Italy Keytruda Market Size
Table 2020-2030 Spain Keytruda Market Size
Table 2020-2030 Belgium Keytruda Market Size
Table 2020-2030 Netherlands Keytruda Market Size
Table 2020-2030 Austria Keytruda Market Size
Table 2020-2030 Poland Keytruda Market Size
Table 2020-2030 Russia Keytruda Market Size
Table 2020-2030 Mea Keytruda Market Size
Table 2020-2030 Mea Keytruda Market Size By Application
Table 2020-2025 Mea Keytruda Key Players Revenue
Table 2020-2025 Mea Keytruda Key Players Market Share
Table 2020-2030 Mea Keytruda Market Size By Type
Table 2020-2030 Egypt Keytruda Market Size
Table 2020-2030 Israel Keytruda Market Size
Table 2020-2030 South Africa Keytruda Market Size
Table 2020-2030 Gulf Cooperation Council Countries Keytruda Market Size
Table 2020-2030 Turkey Keytruda Market Size
Table 2020-2025 Global Keytruda Market Size By Region
Table 2020-2025 Global Keytruda Market Size Share By Region
Table 2020-2025 Global Keytruda Market Size By Application
Table 2020-2025 Global Keytruda Market Share By Application
Table 2020-2025 Global Keytruda Key Vendors Revenue
Table 2020-2025 Global Keytruda Key Vendors Market Share
Table 2020-2025 Global Keytruda Market Size By Type
Table 2020-2025 Global Keytruda Market Share By Type
Table 2025-2030 Global Keytruda Market Size By Region
Table 2025-2030 Global Keytruda Market Size Share By Region
Table 2025-2030 Global Keytruda Market Size By Application
Table 2025-2030 Global Keytruda Market Share By Application
Table 2025-2030 Global Keytruda Key Vendors Revenue
Table 2025-2030 Global Keytruda Key Vendors Market Share
Table 2025-2030 Global Keytruda Market Size By Type
Table 2025-2030 Keytruda Global Market Share By Type

Figure Market Size Estimated Method
Figure Major Forecasting Factors
Figure Keytruda Picture
Figure 2020-2030 North America Keytruda Market Size And Cagr
Figure 2020-2030 South America Keytruda Market Size And Cagr
Figure 2020-2030 Asia & Pacific Keytruda Market Size And Cagr
Figure 2020-2030 Europe Keytruda Market Size And Cagr
Figure 2020-2030 Mea Keytruda Market Size And Cagr
Figure 2020-2025 Global Keytruda Market Size And Growth Rate
Figure 2025-2030 Global Keytruda Market Size And Growth Rate

Research Methodology

  • Market Estimated Methodology:

    Bottom-up & top-down approach, supply & demand approach are the most important method which is used by HDIN Research to estimate the market size.

1)Top-down & Bottom-up Approach

Top-down approach uses a general market size figure and determines the percentage that the objective market represents.

Bottom-up approach size the objective market by collecting the sub-segment information.

2)Supply & Demand Approach

Supply approach is based on assessments of the size of each competitor supplying the objective market.

Demand approach combine end-user data within a market to estimate the objective market size. It is sometimes referred to as bottom-up approach.

  • Forecasting Methodology
  • Numerous factors impacting the market trend are considered for forecast model:
  • New technology and application in the future;
  • New project planned/under contraction;
  • Global and regional underlying economic growth;
  • Threatens of substitute products;
  • Industry expert opinion;
  • Policy and Society implication.
  • Analysis Tools

1)PEST Analysis

PEST Analysis is a simple and widely used tool that helps our client analyze the Political, Economic, Socio-Cultural, and Technological changes in their business environment.

  • Benefits of a PEST analysis:
  • It helps you to spot business opportunities, and it gives you advanced warning of significant threats.
  • It reveals the direction of change within your business environment. This helps you shape what you’re doing, so that you work with change, rather than against it.
  • It helps you avoid starting projects that are likely to fail, for reasons beyond your control.
  • It can help you break free of unconscious assumptions when you enter a new country, region, or market; because it helps you develop an objective view of this new environment.

2)Porter’s Five Force Model Analysis

The Porter’s Five Force Model is a tool that can be used to analyze the opportunities and overall competitive advantage. The five forces that can assist in determining the competitive intensity and potential attractiveness within a specific area.

  • Threat of New Entrants: Profitable industries that yield high returns will attract new firms.
  • Threat of Substitutes: A substitute product uses a different technology to try to solve the same economic need.
  • Bargaining Power of Customers: the ability of customers to put the firm under pressure, which also affects the customer's sensitivity to price changes.
  • Bargaining Power of Suppliers: Suppliers of raw materials, components, labor, and services (such as expertise) to the firm can be a source of power over the firm when there are few substitutes.
  • Competitive Rivalry: For most industries the intensity of competitive rivalry is the major determinant of the competitiveness of the industry.

3)Value Chain Analysis

Value chain analysis is a tool to identify activities, within and around the firm and relating these activities to an assessment of competitive strength. Value chain can be analyzed by primary activities and supportive activities. Primary activities include: inbound logistics, operations, outbound logistics, marketing & sales, service. Support activities include: technology development, human resource management, management, finance, legal, planning.

4)SWOT Analysis

SWOT analysis is a tool used to evaluate a company's competitive position by identifying its strengths, weaknesses, opportunities and threats. The strengths and weakness is the inner factor; the opportunities and threats are the external factor. By analyzing the inner and external factors, the analysis can provide the detail information of the position of a player and the characteristics of the industry.

  • Strengths describe what the player excels at and separates it from the competition
  • Weaknesses stop the player from performing at its optimum level.
  • Opportunities refer to favorable external factors that the player can use to give it a competitive advantage.
  • Threats refer to factors that have the potential to harm the player.
  • Data Sources
Primary Sources Secondary Sources
Face to face/Phone Interviews with market participants, such as:
Manufactures;
Distributors;
End-users;
Experts.
Online Survey
Government/International Organization Data:
Annual Report/Presentation/Fact Book
Internet Source Information
Industry Association Data
Free/Purchased Database
Market Research Report
Book/Journal/News

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