Cystic Fibrosis Therapeutics Market Insights 2025, Analysis and Forecast to 2030, by Manufacturers, Regions, Technology, Application, Product Type

By: HDIN Research Published: 2025-05-25 Pages: 92
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Cystic Fibrosis Therapeutics Market Summary
Introduction and Market Overview
Cystic fibrosis (CF) therapeutics, including CFTR modulators, pancreatic enzyme supplements, mucolytics, and bronchodilators, address a genetic disorder affecting approximately 105,000 patients globally, with 40,000 in the U.S. and 50,000 in Europe. The market is driven by rising diagnosis rates, with newborn screening increasing detection by 20%, and transformative CFTR modulators like Trikafta, which improve lung function in 90% of F508del patients and reduce hospitalizations by 60%. Early intervention, extended patient lifespans (30% higher survival with early treatment), and supportive policies, with 60% of OECD countries covering CFTR modulators, fuel demand. The global CF therapeutics market is estimated at USD 6.0-10.0 billion in 2025, with a CAGR of 11%-16% through 2030.

Regional Market Trends
 North America: The U.S. leads with widespread newborn screening and Trikafta adoption, while Canada emphasizes CF care access.
 Europe: The UK, Germany, and France drive growth with robust reimbursement for CFTR modulators.
 Asia Pacific: Australia expands CF screening, while Japan focuses on novel therapies.
 Rest of the World: Brazil improves CF care infrastructure, while the Middle East addresses genetic screening.

Distribution Channel Analysis
 Hospital Pharmacies: Expected growth of 11.5%-16.5%, driven by CFTR modulator prescriptions. Trends focus on specialized care.
 Online Pharmacies: Projected growth of 12.0%-17.0%, linked to patient convenience. Advances emphasize digital access.
 Retail Pharmacies: Anticipated growth of 10.5%-15.5%, covering supportive therapies. Trends highlight community-based care.

Type Analysis
 CFTR Modulators: Expected growth of 12.0%-17.0%, valued for transformative outcomes. Trends focus on triple-combination therapies like Vanza.
 Pancreatic Enzyme Supplements: Projected growth of 10.5%-15.5%, essential for digestion. Advances emphasize high-potency formulations.
 Mucolytics: Anticipated growth of 10.0%-15.0%, used for airway clearance. Trends highlight inhalation therapies.
 Bronchodilators: Expected growth of 9.5%-14.5%, suited for symptom relief. Developments prioritize long-acting agents.

Key Market Players
 Vertex Pharmaceuticals: Pioneers CFTR modulators like Trikafta.
 AbbVie: Develops pancreatic enzyme supplements.
 Gilead: Focuses on CF supportive therapies.
 Roche: Provides mucolytics for airway management.
 Sionna Therapeutics: Innovates novel CFTR therapies.

Porter’s Five Forces Analysis
 Threat of New Entrants: Low, due to high R&D costs and regulatory barriers for orphan drugs.
 Threat of Substitutes: Low, as CFTR modulators are unique, though gene therapies pose future competition.
 Bargaining Power of Buyers: Moderate, with insurers negotiating prices, but limited alternatives strengthen providers.
 Bargaining Power of Suppliers: Low, with multiple manufacturers of APIs.
 Competitive Rivalry: Moderate, with Vertex dominating, but emerging players challenge with novel therapies.

Market Opportunities and Challenges
Opportunities:
 Addressing 105,000 CF patients globally.
 Leveraging CFTR modulators, improving outcomes for 90% of F508del patients.
 Utilizing newborn screening, increasing diagnosis by 20%.
 Supporting early intervention, raising survival by 30%.
 Benefiting from 60% OECD reimbursement coverage.
 Expanding research funding, like CFF’s USD 6.6 million investment.
Challenges:
 High costs of CFTR modulators limiting access.
 Regulatory delays for novel therapies.
 Limited CF infrastructure in developing regions.
 Competition from emerging gene therapies.
 Patient adherence issues with complex regimens.
Table of Contents
Chapter 1 Executive Summary
Chapter 2 Abbreviation and Acronyms
Chapter 3 Preface
3.1 Research Scope
3.2 Research Sources
3.2.1 Data Sources
3.2.2 Assumptions
3.3 Research Method
Chapter 4 Market Landscape
4.1 Market Overview
4.2 Classification/Types
4.3 Application/End Users
Chapter 5 Market Trend Analysis
5.1 Introduction
5.2 Drivers
5.3 Restraints
5.4 Opportunities
5.5 Threats
Chapter 6 Industry Chain Analysis
6.1 Upstream/Suppliers Analysis
6.2 Cystic Fibrosis Therapeutics Analysis
6.2.1 Technology Analysis
6.2.2 Cost Analysis
6.2.3 Market Channel Analysis
6.3 Downstream Buyers/End Users
Chapter 7 Latest Market Dynamics
7.1 Latest News
7.2 Merger and Acquisition
7.3 Planned/Future Project
7.4 Policy Dynamics
Chapter 8 Historical and Forecast Cystic Fibrosis Therapeutics Market in North America (2020-2030)
8.1 Cystic Fibrosis Therapeutics Market Size
8.2 Cystic Fibrosis Therapeutics Market by End Use
8.3 Competition by Players/Suppliers
8.4 Cystic Fibrosis Therapeutics Market Size by Type
8.5 Key Countries Analysis
8.5.1 United States
8.5.2 Canada
8.5.3 Mexico
Chapter 9 Historical and Forecast Cystic Fibrosis Therapeutics Market in South America (2020-2030)
9.1 Cystic Fibrosis Therapeutics Market Size
9.2 Cystic Fibrosis Therapeutics Market by End Use
9.3 Competition by Players/Suppliers
9.4 Cystic Fibrosis Therapeutics Market Size by Type
9.5 Key Countries Analysis
9.5.1 Brazil
9.5.2 Argentina
9.5.3 Chile
9.5.4 Peru
Chapter 10 Historical and Forecast Cystic Fibrosis Therapeutics Market in Asia & Pacific (2020-2030)
10.1 Cystic Fibrosis Therapeutics Market Size
10.2 Cystic Fibrosis Therapeutics Market by End Use
10.3 Competition by Players/Suppliers
10.4 Cystic Fibrosis Therapeutics Market Size by Type
10.5 Key Countries Analysis
10.5.1 China
10.5.2 India
10.5.3 Japan
10.5.4 South Korea
10.5.5 Southest Asia
10.5.6 Australia
Chapter 11 Historical and Forecast Cystic Fibrosis Therapeutics Market in Europe (2020-2030)
11.1 Cystic Fibrosis Therapeutics Market Size
11.2 Cystic Fibrosis Therapeutics Market by End Use
11.3 Competition by Players/Suppliers
11.4 Cystic Fibrosis Therapeutics Market Size by Type
11.5 Key Countries Analysis
11.5.1 Germany
11.5.2 France
11.5.3 United Kingdom
11.5.4 Italy
11.5.5 Spain
11.5.6 Belgium
11.5.7 Netherlands
11.5.8 Austria
11.5.9 Poland
11.5.10 Russia
Chapter 12 Historical and Forecast Cystic Fibrosis Therapeutics Market in MEA (2020-2030)
12.1 Cystic Fibrosis Therapeutics Market Size
12.2 Cystic Fibrosis Therapeutics Market by End Use
12.3 Competition by Players/Suppliers
12.4 Cystic Fibrosis Therapeutics Market Size by Type
12.5 Key Countries Analysis
12.5.1 Egypt
12.5.2 Israel
12.5.3 South Africa
12.5.4 Gulf Cooperation Council Countries
12.5.5 Turkey
Chapter 13 Summary For Global Cystic Fibrosis Therapeutics Market (2020-2025)
13.1 Cystic Fibrosis Therapeutics Market Size
13.2 Cystic Fibrosis Therapeutics Market by End Use
13.3 Competition by Players/Suppliers
13.4 Cystic Fibrosis Therapeutics Market Size by Type
Chapter 14 Global Cystic Fibrosis Therapeutics Market Forecast (2025-2030)
14.1 Cystic Fibrosis Therapeutics Market Size Forecast
14.2 Cystic Fibrosis Therapeutics Application Forecast
14.3 Competition by Players/Suppliers
14.4 Cystic Fibrosis Therapeutics Type Forecast
Chapter 15 Analysis of Global Key Vendors
15.1 Vertex Pharmaceuticals
15.1.1 Company Profile
15.1.2 Main Business and Cystic Fibrosis Therapeutics Information
15.1.3 SWOT Analysis of Vertex Pharmaceuticals
15.1.4 Vertex Pharmaceuticals Cystic Fibrosis Therapeutics Sales, Revenue, Price and Gross Margin (2020-2025)
15.2 AbbVie
15.2.1 Company Profile
15.2.2 Main Business and Cystic Fibrosis Therapeutics Information
15.2.3 SWOT Analysis of AbbVie
15.2.4 AbbVie Cystic Fibrosis Therapeutics Sales, Revenue, Price and Gross Margin (2020-2025)
15.3 Gilead
15.3.1 Company Profile
15.3.2 Main Business and Cystic Fibrosis Therapeutics Information
15.3.3 SWOT Analysis of Gilead
15.3.4 Gilead Cystic Fibrosis Therapeutics Sales, Revenue, Price and Gross Margin (2020-2025)
15.4 Roche
15.4.1 Company Profile
15.4.2 Main Business and Cystic Fibrosis Therapeutics Information
15.4.3 SWOT Analysis of Roche
15.4.4 Roche Cystic Fibrosis Therapeutics Sales, Revenue, Price and Gross Margin (2020-2025)
15.5 Alcresta Therapeutics
15.5.1 Company Profile
15.5.2 Main Business and Cystic Fibrosis Therapeutics Information
15.5.3 SWOT Analysis of Alcresta Therapeutics
15.5.4 Alcresta Therapeutics Cystic Fibrosis Therapeutics Sales, Revenue, Price and Gross Margin (2020-2025)
15.6 Chiesi Farmaceutici
15.6.1 Company Profile
15.6.2 Main Business and Cystic Fibrosis Therapeutics Information
15.6.3 SWOT Analysis of Chiesi Farmaceutici
15.6.4 Chiesi Farmaceutici Cystic Fibrosis Therapeutics Sales, Revenue, Price and Gross Margin (2020-2025)
15.7 Merck
15.7.1 Company Profile
15.7.2 Main Business and Cystic Fibrosis Therapeutics Information
15.7.3 SWOT Analysis of Merck
15.7.4 Merck Cystic Fibrosis Therapeutics Sales, Revenue, Price and Gross Margin (2020-2025)
15.8 AstraZeneca
15.8.1 Company Profile
15.8.2 Main Business and Cystic Fibrosis Therapeutics Information
15.8.3 SWOT Analysis of AstraZeneca
15.8.4 AstraZeneca Cystic Fibrosis Therapeutics Sales, Revenue, Price and Gross Margin (2020-2025)
Please ask for sample pages for full companies list
Table Abbreviation And Acronyms
Table Research Scope Of Cystic Fibrosis Therapeutics Report
Table Data Sources Of Cystic Fibrosis Therapeutics Report
Table Major Assumptions Of Cystic Fibrosis Therapeutics Report
Table Cystic Fibrosis Therapeutics Classification
Table Cystic Fibrosis Therapeutics Applications
Table Drivers Of Cystic Fibrosis Therapeutics Market
Table Restraints Of Cystic Fibrosis Therapeutics Market
Table Opportunities Of Cystic Fibrosis Therapeutics Market
Table Threats Of Cystic Fibrosis Therapeutics Market
Table Raw Materials Suppliers
Table Different Production Methods Of Cystic Fibrosis Therapeutics
Table Cost Structure Analysis Of Cystic Fibrosis Therapeutics
Table Key End Users
Table Latest News Of Cystic Fibrosis Therapeutics Market
Table Merger And Acquisition
Table Planned/Future Project Of Cystic Fibrosis Therapeutics Market
Table Policy Of Cystic Fibrosis Therapeutics Market
Table 2020-2030 North America Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 North America Cystic Fibrosis Therapeutics Market Size By Application
Table 2020-2025 North America Cystic Fibrosis Therapeutics Key Players Revenue
Table 2020-2025 North America Cystic Fibrosis Therapeutics Key Players Market Share
Table 2020-2030 North America Cystic Fibrosis Therapeutics Market Size By Type
Table 2020-2030 United States Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Canada Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Mexico Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 South America Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 South America Cystic Fibrosis Therapeutics Market Size By Application
Table 2020-2025 South America Cystic Fibrosis Therapeutics Key Players Revenue
Table 2020-2025 South America Cystic Fibrosis Therapeutics Key Players Market Share
Table 2020-2030 South America Cystic Fibrosis Therapeutics Market Size By Type
Table 2020-2030 Brazil Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Argentina Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Chile Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Peru Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Asia & Pacific Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Asia & Pacific Cystic Fibrosis Therapeutics Market Size By Application
Table 2020-2025 Asia & Pacific Cystic Fibrosis Therapeutics Key Players Revenue
Table 2020-2025 Asia & Pacific Cystic Fibrosis Therapeutics Key Players Market Share
Table 2020-2030 Asia & Pacific Cystic Fibrosis Therapeutics Market Size By Type
Table 2020-2030 China Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 India Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Japan Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 South Korea Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Southeast Asia Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Australia Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Europe Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Europe Cystic Fibrosis Therapeutics Market Size By Application
Table 2020-2025 Europe Cystic Fibrosis Therapeutics Key Players Revenue
Table 2020-2025 Europe Cystic Fibrosis Therapeutics Key Players Market Share
Table 2020-2030 Europe Cystic Fibrosis Therapeutics Market Size By Type
Table 2020-2030 Germany Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 France Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 United Kingdom Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Italy Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Spain Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Belgium Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Netherlands Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Austria Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Poland Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Russia Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Mea Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Mea Cystic Fibrosis Therapeutics Market Size By Application
Table 2020-2025 Mea Cystic Fibrosis Therapeutics Key Players Revenue
Table 2020-2025 Mea Cystic Fibrosis Therapeutics Key Players Market Share
Table 2020-2030 Mea Cystic Fibrosis Therapeutics Market Size By Type
Table 2020-2030 Egypt Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Israel Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 South Africa Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Gulf Cooperation Council Countries Cystic Fibrosis Therapeutics Market Size
Table 2020-2030 Turkey Cystic Fibrosis Therapeutics Market Size
Table 2020-2025 Global Cystic Fibrosis Therapeutics Market Size By Region
Table 2020-2025 Global Cystic Fibrosis Therapeutics Market Size Share By Region
Table 2020-2025 Global Cystic Fibrosis Therapeutics Market Size By Application
Table 2020-2025 Global Cystic Fibrosis Therapeutics Market Share By Application
Table 2020-2025 Global Cystic Fibrosis Therapeutics Key Vendors Revenue
Table 2020-2025 Global Cystic Fibrosis Therapeutics Key Vendors Market Share
Table 2020-2025 Global Cystic Fibrosis Therapeutics Market Size By Type
Table 2020-2025 Global Cystic Fibrosis Therapeutics Market Share By Type
Table 2025-2030 Global Cystic Fibrosis Therapeutics Market Size By Region
Table 2025-2030 Global Cystic Fibrosis Therapeutics Market Size Share By Region
Table 2025-2030 Global Cystic Fibrosis Therapeutics Market Size By Application
Table 2025-2030 Global Cystic Fibrosis Therapeutics Market Share By Application
Table 2025-2030 Global Cystic Fibrosis Therapeutics Key Vendors Revenue
Table 2025-2030 Global Cystic Fibrosis Therapeutics Key Vendors Market Share
Table 2025-2030 Global Cystic Fibrosis Therapeutics Market Size By Type
Table 2025-2030 Cystic Fibrosis Therapeutics Global Market Share By Type

Figure Market Size Estimated Method
Figure Major Forecasting Factors
Figure Cystic Fibrosis Therapeutics Picture
Figure 2020-2030 North America Cystic Fibrosis Therapeutics Market Size And Cagr
Figure 2020-2030 South America Cystic Fibrosis Therapeutics Market Size And Cagr
Figure 2020-2030 Asia & Pacific Cystic Fibrosis Therapeutics Market Size And Cagr
Figure 2020-2030 Europe Cystic Fibrosis Therapeutics Market Size And Cagr
Figure 2020-2030 Mea Cystic Fibrosis Therapeutics Market Size And Cagr
Figure 2020-2025 Global Cystic Fibrosis Therapeutics Market Size And Growth Rate
Figure 2025-2030 Global Cystic Fibrosis Therapeutics Market Size And Growth Rate

Research Methodology

  • Market Estimated Methodology:

    Bottom-up & top-down approach, supply & demand approach are the most important method which is used by HDIN Research to estimate the market size.

1)Top-down & Bottom-up Approach

Top-down approach uses a general market size figure and determines the percentage that the objective market represents.

Bottom-up approach size the objective market by collecting the sub-segment information.

2)Supply & Demand Approach

Supply approach is based on assessments of the size of each competitor supplying the objective market.

Demand approach combine end-user data within a market to estimate the objective market size. It is sometimes referred to as bottom-up approach.

  • Forecasting Methodology
  • Numerous factors impacting the market trend are considered for forecast model:
  • New technology and application in the future;
  • New project planned/under contraction;
  • Global and regional underlying economic growth;
  • Threatens of substitute products;
  • Industry expert opinion;
  • Policy and Society implication.
  • Analysis Tools

1)PEST Analysis

PEST Analysis is a simple and widely used tool that helps our client analyze the Political, Economic, Socio-Cultural, and Technological changes in their business environment.

  • Benefits of a PEST analysis:
  • It helps you to spot business opportunities, and it gives you advanced warning of significant threats.
  • It reveals the direction of change within your business environment. This helps you shape what you’re doing, so that you work with change, rather than against it.
  • It helps you avoid starting projects that are likely to fail, for reasons beyond your control.
  • It can help you break free of unconscious assumptions when you enter a new country, region, or market; because it helps you develop an objective view of this new environment.

2)Porter’s Five Force Model Analysis

The Porter’s Five Force Model is a tool that can be used to analyze the opportunities and overall competitive advantage. The five forces that can assist in determining the competitive intensity and potential attractiveness within a specific area.

  • Threat of New Entrants: Profitable industries that yield high returns will attract new firms.
  • Threat of Substitutes: A substitute product uses a different technology to try to solve the same economic need.
  • Bargaining Power of Customers: the ability of customers to put the firm under pressure, which also affects the customer's sensitivity to price changes.
  • Bargaining Power of Suppliers: Suppliers of raw materials, components, labor, and services (such as expertise) to the firm can be a source of power over the firm when there are few substitutes.
  • Competitive Rivalry: For most industries the intensity of competitive rivalry is the major determinant of the competitiveness of the industry.

3)Value Chain Analysis

Value chain analysis is a tool to identify activities, within and around the firm and relating these activities to an assessment of competitive strength. Value chain can be analyzed by primary activities and supportive activities. Primary activities include: inbound logistics, operations, outbound logistics, marketing & sales, service. Support activities include: technology development, human resource management, management, finance, legal, planning.

4)SWOT Analysis

SWOT analysis is a tool used to evaluate a company's competitive position by identifying its strengths, weaknesses, opportunities and threats. The strengths and weakness is the inner factor; the opportunities and threats are the external factor. By analyzing the inner and external factors, the analysis can provide the detail information of the position of a player and the characteristics of the industry.

  • Strengths describe what the player excels at and separates it from the competition
  • Weaknesses stop the player from performing at its optimum level.
  • Opportunities refer to favorable external factors that the player can use to give it a competitive advantage.
  • Threats refer to factors that have the potential to harm the player.
  • Data Sources
Primary Sources Secondary Sources
Face to face/Phone Interviews with market participants, such as:
Manufactures;
Distributors;
End-users;
Experts.
Online Survey
Government/International Organization Data:
Annual Report/Presentation/Fact Book
Internet Source Information
Industry Association Data
Free/Purchased Database
Market Research Report
Book/Journal/News

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